Alpha Adducin (ADD1) Antibody is a Rabbit Polyclonal against Alpha Adducin (ADD1). Adducins are a family of cytoskeletal proteins encoded by three genes (alpha, beta, and gamma). Adducin acts as a heterodimer of the related alpha, beta, or gamma subunits. The protein encoded by this gene represents the alpha subunit. Alpha- and beta-adducin include a protease-resistant N-terminal region and a protease-sensitive, hydrophilic C-terminal region. Adducin binds with high affinity to Ca(2+)/calmodulin and is a substrate for protein kinases A and C.

Target	Alpha Adducin (ADD1)
Clonality	Polyclonal
Reactivity	Human
Tested Applications	ELISA, WB, IHC
Host	Rabbit
Recommended dilutions	ELISA: 1/20000 - 1/80000, WB: 1/500 - 1/2000, IHC: 1/100 - 1/200. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	A peptide corresponding to the C-terminal region of human alpha Adducin protein.
Isotype	IgG
Form	Lyophilized
Purification	Purified by antigen affinity column chromatography.
Reconstitution	Reconstitute in 100 μl of sterile distilled H2O with 50% glycerol.
Storage	Store at -20 °C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	P35611 (UniProt, ExPASy)
UniProt Entry Name	ADDA_HUMAN
Gene Symbol	ADD1
GeneID	118
OMIM	102680
NCBI Accession	NP_001110.2 NM_001119.4
HGNC	243
KEGG	hsa:118
Ensembl	ENSG00000087274
String	9606.ENSP00000264758
Molecular Weight	Observed MW: 110-120 kDa
Buffer	Prior to lyophilization: 1% BSA and 0.02% NaN3.
Concentration	Lyophilized form: Not applicable. After reconstitution: 1 mg/ml.
Availability	Shipped within 7-15 working days.
Note	This product is for research use only.

Research Articles on Alpha Adducin (ADD1)